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What is the most important information I should know about Zyrtec?

  • Use caution when driving, operating machinery, or performing other hazardous activities. Zyrtec may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
  • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking Zyrtec.
  • While you are taking Zyrtec, do not take other prescription or over-the-counter cough, cold, or allergy medications without first talking to your doctor or pharmacist.

What is Zyrtec?

  • Zyrtec is an antihistamine. Zyrtec blocks the actions of the naturally occurring chemical histamine in the body. Zyrtec is less likely than some other antihistamines to cause side effects such as drowsiness and dizziness.
  • Zyrtec is used to treat the symptoms of allergies such as sneezing; runny nose; itching, tearing, and redness of the eyes; and hives.
  • Zyrtec may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking Zyrtec?

  • Do not take Zyrtec without first talking to your doctor if you have had an allergic reaction to it or to the medication hydroxyzine (Atarax, Vistaril).
  • Before taking Zyrtec, tell your doctor if you have kidney or liver disease. You may need a dosage adjustment or special monitoring during treatment.
  • Zyrtec is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take Zyrtec without first talking to your doctor if you are pregnant or could become pregnant during treatment.
  • Zyrtec passes into breast milk and may affect a nursing baby. Do not take Zyrtec without first talking to your doctor if you are breast-feeding a baby.
  • If you are over 65 years of age, you may be more likely to experience side effects from Zyrtec. Your doctor may prescribe a lower dose of this medication.

How should I take Zyrtec?

  • Take Zyrtec exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take the tablets with a full glass of water.
  • Chew the chewable tablets thoroughly before swallowing.
  • To ensure you get the correct dose, measure the liquid form of Zyrtec with a dose-measuring spoon, cup, or dropper, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.
  • Zyrtec can be taken with or without food.
  • Store Zyrtec at room temperature away from moisture and heat.

What happens if I miss a dose?

  • If you are taking Zyrtec on a regular schedule, take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose.
  • If you are taking Zyrtec as needed, take the missed dose if it is needed, then wait the recommended or prescribed amount of time before taking another dose.

What happens if I overdose?

  • Seek emergency medical attention if an overdose is suspected.
  • Symptoms of a Zyrtec overdose are not well known but may include drowsiness.

What should I avoid while taking Zyrtec?

  • Use caution when driving, operating machinery, or performing other hazardous activities. Zyrtec may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
  • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking Zyrtec.
  • Zyrtec may increase the effects of other drugs that cause drowsiness or dizziness, including antidepressants, alcohol, sedatives (used to treat insomnia), pain relievers, anxiety medicines, muscle relaxants, and other antihistamines. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.
  • While you are taking Zyrtec, do not take other prescription or over-the-counter cough, cold, or allergy medications without first talking to your doctor or pharmacist.

What are the possible side effects of Zyrtec?

  • Stop taking Zyrtec and seek emergency medical attention if you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).
  • Other, less serious side effects may be more likely to occur. Continue to take Zyrtec and talk to your doctor if you experience
    • drowsiness;
    • dizziness;
    • headache; or
    • dry mouth.
  • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Zyrtec?

  • Zyrtec may increase the effects of other drugs that cause drowsiness or dizziness, including antidepressants, alcohol, sedatives (used to treat insomnia), pain relievers, anxiety medicines, muscle relaxants, and other antihistamines. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.
  • While you are taking Zyrtec, do not take other prescription or over-the-counter cough, cold, or allergy medications without first talking to your doctor or pharmacist.
  • Drugs other than those listed here may also interact with Zyrtec. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.
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