What is the most important information I should know about Clomid?

• Use caution when driving, operating machinery, or performing other hazardous activities. Clomid may cause blurred vision or other visual side effects during or shortly after therapy. Notify your doctor immediately if you develop any visual side effects and use caution when performing hazardous activities, especially under conditions of variable lighting.
• Clomid may increase the likelihood of multiple births. Multiple births may carry additional risk both for the mother and for the fetuses.

What is Clomid?

• Clomid stimulates the release of hormones necessary for ovulation to occur.
• Clomid is used to stimulate ovulation (the release of an egg) when a woman's ovaries can produce a follicle but hormonal stimulation is deficient.
• Clomid may also be used for purposes other than those listed in this medication guide.

Who should not take Clomid?

• Do not take Clomid without first talking to your doctor if you
  • might be pregnant;
  • have a thyroid problem or another endocrine disorder;
  • have undiagnosed vaginal bleeding;
  • have endometriosis or endometrial carcinoma;
  • have uterine fibroids;
  • have liver disease;
  • have ovarian cysts or ovarian enlargement not due to polycystic ovarian syndrome; or
  • have any other serious or chronic medical illness.
• You may not be able to take Clomid, or you may require a lower dose or special monitoring if you have any of the conditions listed above.
• Do not take Clomid if you are pregnant. Clomid is in the FDA pregnancy category X. This means that it is known to cause birth defects.
• It is not known whether Clomid pass into breast milk. Do not take Clomid without first talking to your doctor if you are breast-feeding a baby.

How should I take Clomid?

• Use Clomid exactly as directed by your doctor. If you do not understand these directions, ask your doctor, nurse, or pharmacist to explain them to you.
• Take each dose with a full glass of water.
• Clomid is usually taken in 5 day cycles. Follow your doctor's instructions.
• Store Clomid at room temperature, away from direct light, moisture, and heat.

What happens if I miss a dose?

• Contact your doctor if you miss a dose of Clomid.

What happens if I overdose?

• Seek emergency medical attention.
• Symptoms of a Clomid overdose include nausea, vomiting, flushing, blurred vision, visual spots or flashes, and abdominal pain.

What should I avoid while taking Clomid?

• Use caution when driving, operating machinery, or performing other hazardous activities. Clomid may cause blurred vision or other visual side effects during or shortly after therapy. Notify your doctor immediately if you develop any visual side effects and use caution when performing hazardous activities, especially under conditions of variable lighting.

What are the possible side effects of Clomid?

• Stop taking Clomid and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).
• The ovarian hyperstimulation syndrome (OHSS) has been reported to occur in patients receiving Clomid. Symptoms of OHSS include swelling of the hands or legs, abdominal pain and swelling, shortness of breath, weight gain, and nausea or vomiting. OHSS can be fatal. Notify your doctor immediately or seek emergency medical attention if you develop any of these side effects.
• Other side effects may also occur. Notify your doctor if you experience
  • ovarian enlargement presenting as abdominal or pelvic pain, tenderness, pressure, or swelling;
  • flushing;
  • nausea, vomiting, or diarrhea;
  • breast tenderness or discomfort;
  • blurred vision or other visual disturbances;
  • headache; or
  • abnormal uterine bleeding.
• Clomid may increase the likelihood of multiple births. Multiple births may carry additional risk both for the mother and for the fetuses.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Clomid?

• There are no known interactions between Clomid and other medicines. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.